Early detection of chronic kidney disease can save lives and cut costs

(Credit: Unsplash)

This article is brought to you thanks to the collaboration of The European Sting with the World Economic Forum.

Author: Ruud Dobber, Executive Vice President and President, BioPharmaceuticals Business Unit, AstraZeneca

  • Chronic kidney disease affects approximately 700 million people around the world.
  • Without investment in early detection, the cost of kidney failure will continue to spiral.
  • Here are four steps to alleviate the growing pressure on health systems.

Approximately 700 million people worldwide live withchronic kidney disease (CKD) – that’s equivalent to the population of Europe. It is a silent disease in its early stages, contributing to the unacceptably low diagnosis rates. CKD is a progressive disease and it’s divided into five stages based on the level of kidney function – stage 1 indicates normal kidney function to stage 5 kidney failure.

If left untreated, the majority of patients with CKD will die from cardiovascular disease before kidney failure which requires dialysis or transplant. When CKD progresses to kidney failure, it results in significant burden to healthcare expenditures. Many developed countries spend 2-3% of their annual healthcare budget on the treatment of kidney failure, even though those receiving such treatment represent less than 0.1% of the global population.

The impact of kidney failure on patients and their families is brutal. Patients undergoing dialysis will sit on a chair three times a week for sessions that last roughly four hours and many face temporary or permanent loss of earned income. In low and middle-income countries, CKD disproportionately affects younger people, meaning that premature mortality resulting from a lack of access to dialysis may also reduce the labour force and drive household poverty.

Yet, despite this, CKD is rarely prioritized by decision makers. The Global Kidney Health Atlas 2019 found that most countries did not have a national strategy for improving CKD care. We urgently need effective strategies for prevention, early identification and effective management which could slow progression of CKD in high-risk patients, reduce the risk of cardiovascular death and the financial burden incurred by health systems.

At AstraZeneca, we stand with the kidney community. Through our partnerships with the International Society of Nephrology (ISN), regional and local scientific associations, patient advocacy groups, and our efforts to support health care providers to more effectively diagnose and treat CKD, we are providing the necessary tools to reinforce earlier detection and intervention.

World Kidney Day: time to rethink our approach

This year’s World Kidney Day also marks exactly one year since the COVID-19 outbreak was declared a pandemic by the World Health Organisation – a timely moment to stop and reflect on how the virus has impacted those at risk and living with CKD and the sustainability and resilience of the health systems that support them.

CKD is the most prevalent risk factor for severe complications from the virus, and with approximately 20-30% of patients hospitalised with COVID-19 developing kidney failure, hospitals are struggling to meet the demand for dialysis.

Given the enormous costs of dialysis, there is a substantial economic rationale for early CKD detection. And there is no better time to take action than now amidst the pandemic. healthcare

What is the World Economic Forum doing about healthcare value and spending?

Each year, $3.2 trillion is spent on global healthcare making little or no impact on good health outcomes.

To address this issue, the World Economic Forum created the Global Coalition for Value in Healthcare to accelerate value-based health systems transformation.

This council partners with governments, leading companies, academia, and experts from around the world to co-design and pilot innovative new approaches to person-centered healthcare.

Where do we start?

1. Setting clear targets and measuring progress

Governments need to set up a clear goal to reduce the number of patients developing kidney failure and establish a national strategy for improving CKD care. To measure progress, patient registries and development of quality indicators across all stages of CKD are imperative to a successful outcome.

2. Investing in prevention and early detection

CKD can be detected using two simple and inexpensive tests (blood and urine) and patients at risk should be part of early detection programmes for CKD which have been found to be cost-effective. People with diabetes, hypertension, heart disease and family history are at increased risk for developing CKD and depending on the region, it may also be important to consider comorbidities, environmental exposures or genetic risk factors. Yet, currently, only 3% of healthcare expenditure goes to prevention – of which only 20% is spent on early diagnosis.

3. Empowering primary care physicians

With a global shortage of healthcare professionals specializing in CKD care, empowering primary care physicians and developing effective multidisciplinary teams to play a greater role in early detection and management can help reduce the burden on hospitals and health systems.

4. Harnessing the potential of digital health solutions

Technology is another way to ease the strain, while increasing access to care for patients – particularly those in remote areas. Underpinning all of this is a need for continued collaboration and innovation. For example, new diagnostic tests that allow people to measure kidney function from home could reduce the need for visits to the doctor’s office, while allowing patients to take a more active role in their health.

CKD is the perfect example of health systems’ failure to act early when the disease is treatable at much lower cost and with much better outcomes. Kidney failure challenges the sustainability of the health system and it leads to deteriorating health which exposes patients to other diseases such as COVID-19. The socio-economic implications of CKD have been underestimated and investment in prevention and early detection is paramount to tackle this growing burden.

Meaningful improvements require deeper collaboration with patient communities, clinicians, policymakers and industry to ensure we have the right policies and solutions in place. With public and private partnerships, we now have a real opportunity within CKD to shift our focus to build more sustainable and resilient health systems.

the sting Milestones

Featured Stings

Can we feed everyone without unleashing disaster? Read on

These campaigners want to give a quarter of the UK back to nature

How to build a more resilient and inclusive global system

Stopping antimicrobial resistance would cost just USD 2 per person a year

EU-Turkey leaders’ meeting, 9 March 2020

Humanitarian aid: EU mobilises over €18 million for the Central African Republic in 2019

COVID-19: MEPs urge quick action to prevent “huge recession”

Climate change is speeding up. Our response needs to be even faster

Here are 10 of the most urgent health challenges we’ll face in the 2020s, according to WHO

Mining the deep seabed will harm biodiversity. We need to talk about it

Syrian crisis: EU mobilises an overall pledge of €6.9 billion for 2020 and beyond

MEPs approve €585 million to support refugees from Syria

How listening to patients could change the way we tackle cancer

Brexit: MEPs concerned over reported UK registration plans for EU27 citizens

Mergers: Commission opens in-depth investigation into proposed acquisition of DSME by HHIH

How banks should prepare for robots going rogue

Yemen: UN Envoy ‘guilty’ of optimistic hope that war is ‘nearing the end’

How to promote Primary Healthcare to the Young Healthcare Workforce?

Youth unemployment: think out of the box

Where does our food come from? Here’s why we need to know

Human rights are ‘key’ for economic policymaking says UN expert

The Dead Sea is drying up, and these two countries have a plan to save it

European Agenda on Migration four years on: Marked progress needs consolidating in face of volatile situation

TTIP wins Merkel’s endorsement ahead of 2016 tough deadline

“Who do I call if I want to call Europe?” Finally a name and a number to answer Henry Kissinger’s question

How a new encryption technique can help protect privacy amid COVID-19

The energy industry is changing. Are governments switched on?

Rapid action needed for people to meet challenges of changing world of work

Scotland in United Kingdom: It’s either the end or the beginning of the end

MEPs approve EU’s spending in 2017

This is the environmental catastrophe you’ve probably never heard of

‘Eden bonds’: how rewilding could save the climate and your pension

Commission statement on the vaccine export authorisation scheme

This is how the coronavirus is affecting indigenous people – and how tech is bringing them together

It takes far too long for a rare disease to be diagnosed. Here’s how that can change

UN chief expresses solidarity with Indonesian authorities after flash floods kill dozens in Papua

Security of 5G networks: EU Member States complete national risk assessments

November infringements package: key decisions

Addressing the consequences of digitalisation in the Russia & CIS region

College meeting: European Commission reorganises the “Task Force for Relations with the United Kingdom” into the “Service for the EU-UK Agreements”.

10 months were not enough for the EU to save the environment but 2 days are

The European Green Deal must be at the heart of the COVID-19 recovery

European Parliament speaks out against “killer robots”

How much time has the ‘European Union of last chance’ left?

Impacting society with digital ingenuity – World Summit Award proclaiming the top 8 worldwide

Here’s a simple and fair way to end corporate tax abuse

Libya: $202 million needed to bring life-saving aid to half a million people hit by humanitarian crisis

Can the EU assume the mantle of global leadership?

COVID has shown we can be creative under pressure: Stockholm’s mayor on harnessing a city’s people power

The future of the plastics industry is green

General Elections in Spain: Twitter organises the first digital debate to empower young people.

UN Human Rights chief urges Venezuela to halt grave rights violations

Medical education and violence against women: a gap in women’s rights

An open letter to Europe’s leaders

Will satellites destroy our view of space?

“Prevention is better than cure”: the main goal of modern medicine

Youth Forum calls on Parliament to ease entry into Europe for young people

Clean air is good for business

Coronavirus: the truth against the myths

Advice on fighting COVID-19 from the Red Cross, a chemist and academics around the world: Today’s coronavirus updates

EU-UK Trade and Cooperation Agreement: protecting European interests, ensuring fair competition, and continued cooperation in areas of mutual interest

How digital can transform healthcare in Asia for millions of people

Managing and resolving conflicts in a politically inclined group of team members

UNICEF reports uneven progress in 30 years of child rights treaty

More Stings?

Speak your Mind Here

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s