Early detection of chronic kidney disease can save lives and cut costs

(Credit: Unsplash)

This article is brought to you thanks to the collaboration of The European Sting with the World Economic Forum.

Author: Ruud Dobber, Executive Vice President and President, BioPharmaceuticals Business Unit, AstraZeneca


  • Chronic kidney disease affects approximately 700 million people around the world.
  • Without investment in early detection, the cost of kidney failure will continue to spiral.
  • Here are four steps to alleviate the growing pressure on health systems.

Approximately 700 million people worldwide live withchronic kidney disease (CKD) – that’s equivalent to the population of Europe. It is a silent disease in its early stages, contributing to the unacceptably low diagnosis rates. CKD is a progressive disease and it’s divided into five stages based on the level of kidney function – stage 1 indicates normal kidney function to stage 5 kidney failure.

If left untreated, the majority of patients with CKD will die from cardiovascular disease before kidney failure which requires dialysis or transplant. When CKD progresses to kidney failure, it results in significant burden to healthcare expenditures. Many developed countries spend 2-3% of their annual healthcare budget on the treatment of kidney failure, even though those receiving such treatment represent less than 0.1% of the global population.

The impact of kidney failure on patients and their families is brutal. Patients undergoing dialysis will sit on a chair three times a week for sessions that last roughly four hours and many face temporary or permanent loss of earned income. In low and middle-income countries, CKD disproportionately affects younger people, meaning that premature mortality resulting from a lack of access to dialysis may also reduce the labour force and drive household poverty.

Yet, despite this, CKD is rarely prioritized by decision makers. The Global Kidney Health Atlas 2019 found that most countries did not have a national strategy for improving CKD care. We urgently need effective strategies for prevention, early identification and effective management which could slow progression of CKD in high-risk patients, reduce the risk of cardiovascular death and the financial burden incurred by health systems.

At AstraZeneca, we stand with the kidney community. Through our partnerships with the International Society of Nephrology (ISN), regional and local scientific associations, patient advocacy groups, and our efforts to support health care providers to more effectively diagnose and treat CKD, we are providing the necessary tools to reinforce earlier detection and intervention.

World Kidney Day: time to rethink our approach

This year’s World Kidney Day also marks exactly one year since the COVID-19 outbreak was declared a pandemic by the World Health Organisation – a timely moment to stop and reflect on how the virus has impacted those at risk and living with CKD and the sustainability and resilience of the health systems that support them.

CKD is the most prevalent risk factor for severe complications from the virus, and with approximately 20-30% of patients hospitalised with COVID-19 developing kidney failure, hospitals are struggling to meet the demand for dialysis.

Given the enormous costs of dialysis, there is a substantial economic rationale for early CKD detection. And there is no better time to take action than now amidst the pandemic. healthcare

What is the World Economic Forum doing about healthcare value and spending?

Each year, $3.2 trillion is spent on global healthcare making little or no impact on good health outcomes.

To address this issue, the World Economic Forum created the Global Coalition for Value in Healthcare to accelerate value-based health systems transformation.

This council partners with governments, leading companies, academia, and experts from around the world to co-design and pilot innovative new approaches to person-centered healthcare.

Where do we start?

1. Setting clear targets and measuring progress

Governments need to set up a clear goal to reduce the number of patients developing kidney failure and establish a national strategy for improving CKD care. To measure progress, patient registries and development of quality indicators across all stages of CKD are imperative to a successful outcome.

2. Investing in prevention and early detection

CKD can be detected using two simple and inexpensive tests (blood and urine) and patients at risk should be part of early detection programmes for CKD which have been found to be cost-effective. People with diabetes, hypertension, heart disease and family history are at increased risk for developing CKD and depending on the region, it may also be important to consider comorbidities, environmental exposures or genetic risk factors. Yet, currently, only 3% of healthcare expenditure goes to prevention – of which only 20% is spent on early diagnosis.

3. Empowering primary care physicians

With a global shortage of healthcare professionals specializing in CKD care, empowering primary care physicians and developing effective multidisciplinary teams to play a greater role in early detection and management can help reduce the burden on hospitals and health systems.

4. Harnessing the potential of digital health solutions

Technology is another way to ease the strain, while increasing access to care for patients – particularly those in remote areas. Underpinning all of this is a need for continued collaboration and innovation. For example, new diagnostic tests that allow people to measure kidney function from home could reduce the need for visits to the doctor’s office, while allowing patients to take a more active role in their health.

CKD is the perfect example of health systems’ failure to act early when the disease is treatable at much lower cost and with much better outcomes. Kidney failure challenges the sustainability of the health system and it leads to deteriorating health which exposes patients to other diseases such as COVID-19. The socio-economic implications of CKD have been underestimated and investment in prevention and early detection is paramount to tackle this growing burden.

Meaningful improvements require deeper collaboration with patient communities, clinicians, policymakers and industry to ensure we have the right policies and solutions in place. With public and private partnerships, we now have a real opportunity within CKD to shift our focus to build more sustainable and resilient health systems.

the sting Milestones

Featured Stings

Can we feed everyone without unleashing disaster? Read on

These campaigners want to give a quarter of the UK back to nature

How to build a more resilient and inclusive global system

Stopping antimicrobial resistance would cost just USD 2 per person a year

Thousands of Syrians in ‘life and death’ struggle amid harsh conditions in remote desert camp, UN warns

Meet the Junior Enterprise network at JEWC 2014!

Brussels to point the finger to Washington for lack of commitment over TTIP

European Defence Fund: EU funds new joint research and industrial projects

Plan for troop pullback ‘now accepted’ by rival forces around key Yemen port, but fighting intensifying elsewhere, Security Council warned

New malaria vaccine trial in Malawi marks ‘an innovation milestone’, declares UN health agency

Progress in medical research: leading or lagging behind?

Yemen talks: Truce agreed over key port city of Hudaydah

Girls hold the key to Zambia’s future

New UN report shows record number of children killed and maimed in conflict

COVID-19 threatens the developing world’s small businesses. This is how to save them

ECB to people: Not responsible if you lose money on Bitcoin, your governments are

Bioethics: how to recover trust in the doctor-patient relationship

ECB with an iron hand disciplines the smaller Eurozone member states; latest victim: Greece

Barcelona’s ‘superblocks’ could save lives and cut pollution, says report

This is how we can save millions of people from extreme poverty after COVID-19

Governments should step up their efforts to give people skills to seize opportunities in a digital world

Unity, regional cooperation and international support needed for Horn of Africa to develop sustainably

The shrinking Arctic ice protects us all. It’s time to act

International World Summit Award calls for outstanding digital applications with impact on society from 178 UN member states

Chinese Premier Li Keqiang’s speech from World Economic Forum’s Annual Meeting of New Champions

Booking.com commits to align practices presenting offers and prices with EU law following EU action

Science leads the response to COVID-19. These 25 scientists are tackling the other global challenges

Europe’s forests are booming. Here’s why.

UN’s Bachelet rejects Sri Lankan official’s ‘spin’ on Human Rights Council encounter, urges reforms

Global South cooperation ‘vital’ to climate change fight, development, Guterres tells historic Buenos Aires summit

Ten UN peacekeepers killed in a terrorist attack in northern Mali

Yemen war: UN chief urges good faith as ‘milestone’ talks get underway in Sweden

Lockdown is the world’s biggest psychological experiment – and we will pay the price

State aid: Commission approves €511 million Italian scheme to compensate commercial rail passenger operators for damages suffered due to coronavirus outbreak

4 ways to deliver social justice during the COVID-19 recovery

This Brooklyn farm company is training a new generation of urban farmers

Why vaccines are not just for children

Online radio and news broadcasts: Parliament and Council reach deal

World’s Press Calls on the United Kingdom to Address Press Freedom Concerns

Turkey: Commission continues humanitarian support for refugees

New UN forestry project bids to help countries meet climate change commitments

Conflict prevention, mediation: among ‘most important tools’ to reduce human suffering, Guterres tells Security Council

5 ocean success stories to chase away the blues

Coronavirus: Pandemic alert should be trigger for countries to do more against COVID-19

Financial services are changing. Here’s how

Thursday’s Daily Brief: Climate crisis and food risks, fresh violence threat for millions of Syrians, calls for calm in Kashmir

The application that encourages us to be heroes

EU shapes its ambitious strategy on India

Chart of the day: When do young Europeans leave home?

Dear Davos: time to declare an emergency opportunity for people and planet

EU Parliament raises burning issues over the FTA with the US

How the world can gear up for the fight against cancer

The World Health Organization has called on countries to ‘test, test, test’ for coronavirus – this is why

Key quotes from China’s Premier Li on COVID-19, the economy and US relations

“ASEM: Global Partners for Global Challenges”, a Sting Exclusive by China’s Ambassador to the EU

There is no patient safety without healthcare workers’ safety

Safer roads: More life-saving technology to be mandatory in vehicles

Canada has the most comprehensive and elaborate migration system, but some challenges remain

Global hunger is on the rise. These simple steps could help eradicate it

The Europe we want: Just, Sustainable, Democratic and Inclusive

Ambassador Zhang Ming Attends the EP Debate on China-EU Relations and Answers Questions

Asia’s plastic problem is choking the world’s oceans. Here’s how to fix it

Guterres censures terrorist attacks in Nigeria, pledges UN ‘solidarity’

UN Mission in Haiti calls on protestors, authorities, to refrain from violence

More Stings?

Advertising

Speak your Mind Here

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s