These are the top 10 global causes of death – but two diseases are in decline

(Credit: Unsplash)

This article is brought to you thanks to the collaboration of The European Sting with the World Economic Forum.

Author: Sean Fleming, Senior Writer, Formative Content


  • Heart diseases and stroke are two of the biggest killers, according to WHO’s 2019 report on the most common causes of death worldwide.
  • There have been encouraging improvements, with deaths from HIV/Aids and tuberculosis in decline.
  • Alzheimer’s is still a growing problem and affects more women than men.
  • Meanwhile, COVID-19 may be disrupting immunization against diseases like measles, cholera and polio.

While the world is still reeling from the coronavirus pandemic, many other common causes of early death are in retreat – including HIV/Aids and tuberculosis.

In its latest report, “Leading causes of death and disability,” the World Health Organization (WHO) has examined data from 2000-2019 to track trends in life-limiting and life-shortening illness and injury. The data does not, however, contain information relating to COVID-19, as it predates the pandemic. As such, this report gives us a snapshot of global health in the pre-pandemic world.

There are already concerns that diverting medical resources toward the current health crisis has led to a worsening situation with other illnesses and diseases.

Last year, UNICEF said it was worried about the confluence of COVID-19 cases and ongoing outbreaks of diseases like measles, cholera and polio. Several countries were already tackling these and other deadly diseases when the pandemic struck, including Afghanistan, the Democratic Republic of Congo, Somalia, the Philippines, Syria and South Sudan.

A graph to show the worlds leading causes of death
HIV is no longer a global top ten cause of death. Image: Statista

Heart disease remains the number-one killer

The leading cause of death in the world in 2019 was ischaemic heart disease, also known as coronary heart disease, the WHO report found. It was responsible for 16% of total deaths and since 2000 has seen the largest increase in mortalities, killing 8.9 million people in 2019.

The top four causes of death in 2019 were the same for men and women:

  • Ischaemic heart disease
  • Stroke
  • Chronic obstructive pulmonary disease
  • Lower respiratory infections

In men, the fifth most common cause of death in 2019 were lung cancers and other trachea/bronchus-related ailments. For women, it was Alzheimer’s disease and other forms of dementia.

“These neurological disorders kill more females than males, with about 80% more deaths and 70% more DALYs for women than for men,” the report states.

DALYs are disability-adjusted life years, a measure that “combines years of life lost due to premature mortality (YLLs) and years of life lost due to time lived in states of less than full health, or years of healthy life lost due to disability (YLDs)”.

The life-expectancy gap

In the period 2000-2019, average global life expectancy rose by more than six years – from 66.8 years in 2000 to 73.4 in 2019. But there is a gap between overall life expectancy and healthy life expectancy, according to the report.

That measure has increased by 8%, from 58.3 years in 2000 to 63.7 in 2019. This indicates there is a point at which health, and possibly quality of life, start to diminish – currently lasting almost 10 years.

Diabetes was found to have the largest impact on DALYs, the WHO says, increasing by 80% between 2000 and 2019. While DALYs caused by Alzheimer’s disease and other forms of dementia have almost doubled.

Optimistic signs

One significant downward trend has been the effect of HIV on DALYs, which dropped by 50%. HIV/Aids has disappeared from the top 10 causes of death, globally – going from 8th place in 2000 to 19th last year.

Another notable difference in HIV/Aids over the period has been the gender split of those it has killed. Since 2000, there has been a 55% decline in deaths among women. In 2000, there were 38,000 fewer women who died from HIV/Aids than men. By 2019, that difference had grown to 90,000.

There has also been progress with tuberculosis (TB), which dropped from seventh place in 2000 to 13th in 2019. Globally, deaths from TB have reduced by 30%. But it is still a problem in many poorer parts of the world, and is in the top 10 causes of death in Africa and South-East Asia.


Discover more from The European Sting - Critical News & Insights on European Politics, Economy, Foreign Affairs, Business & Technology - europeansting.com

Subscribe to get the latest posts sent to your email.

Interesting reads

© UNICEF/Nyan Zay Htet Recent disruptions to energy supplies and global supply chains have reverberated across development and humanitarian sectors, including relief efforts in Myanmar, where millions remain in need of assistance.

Global energy and trade disruption pushing millions towards poverty

This article is published in association with United Nations. Disruptions to global energy supplies and trade corridors are driving up the cost of food, transport and essential goods worldwide, slowing economic growth and increasing pressure on vulnerable households and debt-strapped developing countries. The warnings came during a special meeting of the UN Economic and Social Council […]
UN Photo/Eskinder Debebe UN Relief Chief Tom Fletcher (centre) along with Ambassador Mike Waltz (right) and Jeremy P. Lewin of the United States hold a joint press briefing on funding to the humanitarian system.

UN welcomes $1.8 billion US boost for humanitarian operations

This article is published in association with United Nations. An additional $1.8 billion in US humanitarian funding will allow the United Nations and its partners to expand emergency relief operations reaching millions of people worldwide, as rising global needs and funding shortfalls force aid agencies to scale back assistance. The funding announcement, made on Wednesday by […]
© WHO/Hanan Balkhy Displaced families are living in overcrowded tents and makeshift shelters, surrounded by waste and debris, with limited access to safe water and sanitation services.

World News in Brief: Mounting waste in Gaza, drone attacks in Sudan, aid truck struck in Ukraine

This article is published in association with United Nations. Mounting waste and limited access to sanitation sites are deepening health risks for families across Gaza, as humanitarian workers warn that overcrowded dumping areas and worsening living conditions threaten vulnerable communities. Ramiz Alakbarov, UN’s top aid official in Occupied Palestinian Territory visited a dumping site in Gaza […]
This article was exclusively written for The European Sting by Mr. Franco Miguel Nodado, a 4th-year medical student from the Philippines. He is affiliated with the International Federation of Medical Students Associations (IFMSA), cordial partner of The Sting. The opinions expressed in this piece belong strictly to the writer and do not necessarily reflect IFMSA’s view on the topic, nor The European Sting’s one.

Autism Spectrum Disorders in Global Health: Bridging the Gap in  Awareness, Early Diagnosis, and Inclusive Care 

This article was exclusively written for The European Sting by Ms. Georgia Maria Vardalachaki, a medical student from the Medical University of Crete, Greece. She is affiliated with the International Federation of Medical Students Associations (IFMSA), cordial partner of The Sting. The opinions expressed in this piece belong strictly to the writer and do not necessarily reflect IFMSA’s […]
© WHO/Hedinn Halldorsson WHO Director-General Tedros and a health expert during operations involving the MV Hondius off Tenerife amid the hantavirus response.

Hantavirus-hit ship evacuation completed as quarantines begin

This article is published in association with United Nations. The passengers and crew have disembarked from the hantavirus-hit cruise ship MV Hondius in Tenerife and many have returned to their home countries, as the UN World Health Organization (WHO) said the operation demonstrated a “triumph of solidarity”. The repatriation effort, coordinated by Spanish authorities with support […]
© NASA The Strait of Hormuz which separates the United Arab Emirates and Iran is a strategically important shipping route

Strait of Hormuz de-escalation is urgent, says UN chief

This article is published in association with United Nations. As the Strait of Hormuz crisis deepens and tensions between Iran and the United States remain unresolved, oil prices rose again early Monday, prompting the UN Secretary-General to call for a peaceful resolution and warn of the widening fallout across Africa and beyond. “My strong appeal is […]
This article is published in association with United Nations.

Ukraine: Over 3,000 attacks on healthcare since full-scale Russian invasion

This article is published in association with United Nations. The World Health Organization (WHO) has verified more than 3,000 attacks on healthcare in Ukraine since Russia launched its full-scale invasion in February 2022, the UN agency reported on Friday. “During 1,534 days of war, Ukraine’s healthcare system has experienced repeated attacks,” it said.  Every aspect of the system has been […]
WHO Passengers from MV Hondius assisted by Spanish and WHO health teams after disembarking.

Passengers leave hantavirus-hit cruise ship in Tenerife as WHO says outbreak ‘not another COVID’

This article is published in association with United Nations. Passengers and crew from the cruise ship MV Hondius began disembarking in Tenerife on Sunday under a tightly coordinated international health operation led by Spanish authorities and the World Health Organization (WHO), as officials sought to reassure the public that the outbreak “is not another COVID.” The […]
Nuclear energy in the Middle East: A realistic choice or a risk?

Nuclear energy in the Middle East: A realistic choice or a risk?

This article is published in association with United Nations. As global electricity demand grows, so does the popularity of nuclear energy. In the Middle East, several countries are evaluating or advancing nuclear power projects, balancing weighty issues such as regional security, climatic conditions and international cooperation. “Nuclear energy is at the intersection of energy demands, technological […]
© NASA The Strait of Hormuz which separates the United Arab Emirates and Iran is a strategically important shipping route

Bahrain and US float Security Council resolution on the Strait of Hormuz

This article is published in association with United Nations. Bahrain and the United States have circulated a draft Security Council resolution calling for Iran to cease attacks in the Strait of Hormuz, their ambassadors outlined to journalists at UN Headquarters in New York on Thursday. The text is supported by Kuwait, Qatar, Saudi Arabia and the […]
© CDC An enhanced microscopic image shows the Hantavirus.

Hantavirus outbreak: Another passenger contracts disease

This article is published in association with United Nations. It’s been confirmed that another passenger from the cruise liner linked to the outbreak of hantavirus has contracted the disease, which has claimed the lives of three people on board and sparked an international alert coordinated by the UN World Health Organization (WHO). The individual, who is […]
This article is published in association with United Nations.

UN warns of worsening human rights crisis in Mali after deadly attacks

This article is published in association with United Nations. The human rights situation in Mali is rapidly deteriorating following coordinated attacks by armed groups across the country, with civilians killed, displaced and cut off from food and aid, UN rights office OHCHR said on Tuesday. The violence, which erupted on 25 and 26 April, saw large-scale […]
© UNICEF A damaged ambulance in Tebnine in southern Lebanon.

In Lebanon, the same fears and dangers persist despite ceasefire: UNHCR

This article is published in association with United Nations. Death and destruction have continued unabated in Lebanon while communities are still unable to return to their homes despite a ceasefire that began on 17 April, humanitarians said on Tuesday. “Civilians in the south of Lebanon and parts of the Bekaa [Valley] are really living with the […]
© Unsplash/Planet Volumes A computer-generated image shows the Strait of Hormuz.

Uncertainty continues over safety in the Strait of Hormuz

This article is published in association with United Nations. Amid claims and counter-claims of strikes and confrontations in the crucial Strait of Hormuz between Iran and the United States, UN maritime officials continue to urge vessels to exercise “maximum caution”. “We are aware of the reports but do not have further details. We continue to urge […]
© ADB/Ariel Javellana Women farmers in India sell wheat grain and buy fertilizer with the proceeds.

Middle East crisis puts aid, food, fuel further out of reach for millions already struggling – UN agencies

This article is published in association with United Nations. As the Middle East crisis continues the humanitarian fallout is worsening, with aid route disruptions and food and fuel price hikes wrecking the lives and the rights of the most vulnerable people worldwide, UN agencies warned on Friday. Heightened insecurity and instability around key Gulf routes, including […]
© Unsplash/Angus Gray Ship transits through the Strait of Hormuz have dropped by over 90 per cent since the crisis escalated in late February 2026.

Hormuz crisis strangling global economy, Guterres warns, demanding solutions to end stalemate

This article is published in association with United Nations. The escalating crisis in the Strait of Hormuz could push tens of millions into poverty, trigger a surge in global hunger and even tip the world towards recession, the UN Secretary-General warned on Thursday. António Guterres decried the restrictions on free passage through the crucial chokepoint which […]
This article is published in association with United Nations.

AI in advertising risks fuelling information crisis, UN warns

This article is published in association with United Nations. With spending on advertising topping $1 trillion a year worldwide, the United Nations on Wednesday highlighted the untapped power of major brands to shape the future of Artificial Intelligence, warning that a failure to act could deepen a global information integrity crisis. In a new brief titled […]
This article is published in association with United Nations.

2015 nuclear deal ‘no basis’ for any new agreement with Iran

This article is published in association with United Nations. The 2015 nuclear accord with Iran cannot be the starting point for a new agreement with the country, the head of the International Atomic Energy Agency (IAEA) said on Wednesday in New York.  Rafael Mariano Grossi was speaking during a press conference at UN Headquarters held on […]
Credit:Unsplash)

From Hormuz to Lebanon, crisis reverberates through trade routes, upending humanitarian networks

© WHO/Hanan Balkhy In Gaza displaced families are living in overcrowded tents and makeshift shelters, surrounded by waste and debris, with limited access to safe water and sanitation services. This article is published in association with United Nations. Disruptions in the Strait of Hormuz continue to send shockwaves through global food systems, the UN Food and Agriculture […]

Why don't you drop your comment here?

Go back up

Discover more from The European Sting - Critical News & Insights on European Politics, Economy, Foreign Affairs, Business & Technology - europeansting.com

Subscribe now to keep reading and get access to the full archive.

Continue reading

Discover more from The European Sting - Critical News & Insights on European Politics, Economy, Foreign Affairs, Business & Technology - europeansting.com

Subscribe now to keep reading and get access to the full archive.

Continue reading

The European Sting – Critical News & Insights on European Politics, Economy, Foreign Affairs, Business & Technology – europeansting.com